2011年4月24日 星期日

Seeing the light

Seeing the light
There are more than 1 million blind people in the U.S., and about 100,000 of those lost their sight due to retinitis pigmentosa,This is also known as your return on investment ledbright or ROI. It is important to spread the ROI over the life of the LED lamp life to truly see the short and long-term energy and maintenance savings. a disease that destroys light-sensitive cells in the retina.

There is currently no cure for retinitis pigmentosa, but scientists are working on ways to restore vision by making other cells of the retina, which are spared by the disease, sensitive to light. In a new study of mice, researchers at the University of Southern California (USC) used technology developed by a consortium of institutions,Although police doesn't like it very much but one thing is certain, that your car will certainly stand out from the rest lightonsale vehicles on the road You don't have to make something "hardcore". including MIT,Rolled copper is obtained by squeezing led spotlight the copper foil, which is characterized by: a good degree of resistance to bending, but weaker than the electrical conductivity of copper is mainly used for clamshell camera phone and the like. From the exterior view, copper red, yellow copper rolling to do just that. By inducing light sensitivity in other cells of the retina, they brought back enough vision for the mice to navigate a maze.

Key to the work is a technology called optogenetics, co-invented by MIT's Ed Boyden, who is an author of a paper on the work appearing in the April 19 online edition of the journal Molecular Therapy. Boyden says the study, led by Alan Horsager of USC's Institute for Genetic Medicine, offers hope that optogenetics could eventually be used to restore sight in humans.

“We don’t know for sure what the animals are consciously seeing, but this study indicates that the mice can make cognitive use of their visual information,” says Boyden, an assistant professor at the MIT Media Lab and member of the McGovern Institute for Brain Research at MIT.

Retinitis pigmentosa can be caused by any one of more than 100 different genetic mutations, each of which leads to the gradual destruction of light-sensitive cells called photoreceptors. Photoreceptors — of which there are two types, rods and cones — form the outermost layer of the retina. They convert light into electrical signals, which are sent to neurons in the retina’s middle layer known as bipolar cells. Bipolar cells send visual information to the inner layer,You want someone that has the experience in LED lighting to guide you to the right product shinebright that is best suited to your project. made up of ganglion cells, which then connect to the brain via the optic nerve.

Optogenetics offers the ability to bypass damaged photoreceptors. The technology involves genetically engineering other types of cells to respond to light by adding genes that code for proteins called channelrhodopsins, which normally sit in the photoreceptor cell membrane. Those channels, which are activated by light, control the flow of ions (charged molecules) into or out of the cell. When light strikes the cell,You want someone that has the experience in LED lighting to guide you to the right product shinebright that is best suited to your project. the channels can open or close, either stimulating or suppressing the flow of ions and thus the electrical activity of the cell.

“It’s a very targeted approach that maintains the natural processing of the retina,” Horsager says. “There is a lot more to understand, but initial indications suggest we have developed something that can have enormous benefit to people. Preclinical studies are the next step to determine the potential therapeutic benefit for humans.”

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